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Updated: May 21, 2025

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
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M6A甲基化调节剂METTL3和ALKBH5是EGFR突变NSCLC的危险因素

Yaofeng Zhi1, Silin Liu1,2, Xuefei Chang1,2

  • 1Clinical Experimental Center, Jiangmen Engineering Technology Research Center of Clinical Biobank and Translational Research, Jiangmen Key Laboratory of Precision and Clinical Translation Medicine, Jiangmen Central Hospital, China.

Cancer control : journal of the Moffitt Cancer Center
|May 17, 2025
PubMed
概括

与N6-甲基氨酸 (m6A) 相关的蛋白质METTL3和ALKBH5在具有表皮生长因子受体 (EGFR) 突变的非小细胞肺癌 (NSCLC) 中升高. 这些蛋白质的高表达表明治疗EGFR-TKI的患者的预后较差.

关键词:
在 ALKBH5H5 中在 EGFR 突变的过程中,在METTL3中,METTL3是METTL3的第一个类型.非小细胞肺癌的肺癌.预后 预后 预后

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