两种基于酒精的手术消毒剂之间使用手套汁技术的短期杀菌性质不同
Katrijn D Whisenant1, Holly L Stewart1, Donna Kelly2,3
11Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA.
概括
这两种基于酒精的洗手剂都立即减少了细菌的数量. 阿瓦加德的疗效维持了一个小时,与斯特里不同,这使得它更适合更长时间的手术.
科学领域:
- 微生物学 微生物学
- 感染控制 感染控制
背景情况:
- 医疗保健相关的感染需要有效的手部卫生.
- 基于酒精的洗手剂对于减少微生物负载至关重要.
研究的目的:
- 为了比较两种基于酒精的手消毒剂的疗效:阿瓦加德 (61% 乙醇,1% 素酸盐) 和斯特里 (85% 乙醇).
- 用手套果汁方法评估细菌殖民地数量减少,立即和应用后一个小时.
主要方法:
- 有8名参与者的前性临床试验.
- 用手套汁取细菌殖民地样本,在消毒剂应用前和之后从手上计数细菌殖民地.
- 在Avagard和Sterillium之间的殖民地形成单位 (CFU) 中的log10降低在即时和1小时时间点的比较.
主要成果:
- 在施用后立即,Sterillium和Avagard都显示出显著的CFU减少.
- 阿瓦加德在应用后1小时的标志上显示了持续的细菌减少.
- 结果基于7名参与者,因为缺少数据点.
结论:
- 这两种手消毒剂都是有效的立即消毒剂.
- 与Sterillium相比,Avagard提供了更长时间的细菌减少.
- 建议在超过一个小时的程序中使用Avagard,或者当Sterillium的重新应用是不可行的时.
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