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行政卫生数据案例定义的有效性,用于识别多囊卵巢综合征:系统性审查和元分析

Sophie Hu¹, Sophie Lalonde-Bester², Jenna Salem³

¹Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada.

Human reproduction (Oxford, England)

|May 17, 2025

概括

这次审查发现,在健康数据中对多囊卵巢综合征 (PCOS) 的定义方面存在重大差距. 为了准确的PCOS人口层面研究,需要标准化定义.

科学领域:

生殖内分泌学生殖内分泌学
医疗信息学医疗信息学
流行病学流行病学

背景情况:

行政卫生数据对于人口层面的健康结果和疾病流行病学研究具有价值.
目前尚不清楚现有的行政卫生数据对多囊卵巢综合征 (PCOS) 的病例定义的有效性.

研究的目的:

与参考标准相比,评估公布的PCOS行政健康数据病例定义的有效性.

主要方法:

通过使用MEDLINE和EMBASE数据库对2023年7月为止的英语文章进行了系统的文献审查.
两个独立审查员选了研究,提取了数据,并评估了有效性. 进行了随机效应元分析,以组合有效性措施.

主要成果:

包括四项研究,采用了各种各样的PCOS病例定义 (罗德丹标准,自我报告,临床黄金标准).
病例定义常用的国际疾病分类 (ICD) 代码256.4和E28.2.2.
积极的预测值 (PPVs) 从30%到96%不等,ICD基于代码的定义的聚合PPV为88%. 在一项研究中,报告的灵敏度为50%.

结论:

审查发现了有限的验证研究和PCOS病例定义在行政数据中的精度指数.
目前的PCOS病例定义存在显著的差距和变异性.
标准化的病例定义和在各种数据集中的进一步验证对于未来的PCOS研究至关重要.

关键词:

在ICD-9中,它被列为ICD-9.在PCOS中,PCOS是PCOS.行政数据行政数据案例定义案例定义在内分泌学内分泌学.健康数据健康数据多囊性卵巢综合征多囊性卵巢综合征灵敏度灵敏度灵敏度灵敏度灵敏度特殊性的特异性系统性审查系统性审查

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