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Updated: May 20, 2025

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评估两种嗅觉训练方法,用于COVID-19后的嗅觉丧失:古典和强化训练方法

V Masson¹, P L Nguyen-Thi², P Gallet¹

¹Service d'ORL et chirurgie cervico-faciale, hôpitaux de Brabois, CHRU de Nancy, Allée du Morvan, 54500 Vandœuvre-les-Nancy, France.

European annals of otorhinolaryngology, head and neck diseases

|May 17, 2025

概括

与标准方法相比,强化嗅觉训练并没有改善COVID-19后持续的嗅觉丧失的恢复. 随着时间的推移,对训练的坚持下降,这表明这两种方案在管理嗅觉功能障碍方面都有局限性.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
神经学神经学
传染性疾病传染性疾病

背景情况:

传染后嗅觉障碍,特别是在COVID-19之后,是一个重大的临床挑战.
嗅觉训练,通常使用4味道协议,是管理嗅觉功能障碍的基石.
更密集的嗅觉训练方案的有效性仍未得到充分研究.

研究的目的:

为了比较密集的8气味嗅觉训练方案与经典的4气味方案的有效性,用于COVID-19后的持续性异位症.
用不同的嗅觉训练强度来评估持久性松症的康复机会.

主要方法:

一项前性随机临床试验,涉及COVID-19后持久性异位症患者 (5周至12个月).
两组接受了经典的4气味或8个月的密集的8气味嗅觉训练方案.
嗅觉在基线,4个月和8个月使用Sniffin' Sticks测试,DynaChron问卷和视觉模拟尺度 (VAS) 进行评估.

主要成果:

这两种嗅觉训练方案都导致了主观嗅觉评估 (VAS) 的显著改善.
在心理物理测试中,古典训练组和强化训练组之间没有观察到嗅觉恢复的显著差异.
患者对培训计划的坚持在4个月后显著下降.

结论:

密集的嗅觉训练 (8 气味协议) 与经典的4 气味协议相比,对于持续的COVID-19 相关的dysosmia,没有提供更好的嗅觉恢复.
这些发现表明,在嗅觉训练中增加气味的数量并不能提高这种情况的恢复率.
随着时间的推移减少的坚持凸显了嗅觉训练方案长期有效性的潜在障碍.

关键词:

在 COVID-19 疫情中,这就是DynaChron.嗅觉培训嗅觉培训嗅觉培训后病毒性无氧化和低氧化.这就是SARS-CoV-2病毒.嗅探棒子测试试验这就是VAS VAS.

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