肺栓塞患者心率变化的短期预后值:两中心队列研究
Junjie Mao1, Chao Guan1, Jun Zhang2
1Department of Respiratory and Critical Care Medicine, the Central Hospital of Xuhui District, Shanghai, China.
Clinical therapeutics
|May 17, 2025
概括
减少心率变化 (HRV) 预测肺血栓栓塞 (PTE) 的不良结果. 这项研究表明,HRV是PTE患者30天重大心血管不良事件 (MACE) 的独立风险因素.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 生物医学工程 生物医学工程
背景情况:
- 肺血栓塞栓症 (PTE) 是一种常见的急性心血管综合征,具有重大风险.
- 心率变化 (HRV) 是已知的不良事件预后指标.
- 在PTE中HRV的预后值需要进一步调查.
研究的目的:
- 评估HRV在预测PTE患者主要心血管不良事件 (MACE) 的30天预后效用.
- 调查HRV和PTE结果之间的相关性.
- 确定HRV是否可以帮助PTE患者的风险分层.
主要方法:
- 对170名PTE患者和174名对照进行了回顾性队列研究.
- 24小时的霍尔特记录和时间域HRV分析.
- 使用ROC,Cox回归和Kaplan-Meier分析评估HRV和MACE之间的关联.
主要成果:
- 与对照组相比,PTE患者的时间域HRV显著降低.
- 降低HRV与PTE患者的MACE风险增加有关 (逻辑等级P<0.05).
- HRV指标,包括正常到正常RR间隔的标准偏差,独立预测MACE.
结论:
- HRV是PTE30天不良结果的独立风险因素.
- 降低HRV与PTE患者的MACE风险增加有关.
- 人力资源可视化可以成为PTE管理中风险分层的一个有价值的工具.
相关概念视频
Pulse rhythm
737
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
737
Assessment of Ventilation I: Respiratory Rate
975
Assessment of Ventilation
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
975
Acute Respiratory Failure-IV
115
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
115
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
73
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
73


