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Updated: May 21, 2025

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迪奥斯对抗甲型流感病毒的抗病毒潜力

Umarqayum AbuBakar1, Zhao Xuan Low2, Muhammad Zhafran Mohd Aris3

  • 1Institute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia. umarqayum@um.edu.my.

Scientific reports
|May 17, 2025
PubMed
概括

一种黄类化合物迪奥斯有效抑制流感A型病毒 (IAV) 复制,并显示出预防作用. 这种天然化合物还可以增强抗病毒基因表达并调节宿主免疫力,为新的流感A病毒疗法提供了有希望的途径.

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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