在新生儿败血症评估中获得阳性血液培养的时间
Emily Willey1, Michelle Mitchell2, Carey Ehlert2
1Children's Wisconsin, Milwaukee, WI, USA. ewilley@childrenswi.org.
概括
对于被评估为败血症的新生儿,血液培养通常在36小时内呈阳性. 这一发现表明,在36小时后,在看起来健康的婴儿中,可以安全地停止使用抗生素,而这些婴儿具有负面培养.
科学领域:
- 新生儿医学 新生儿医学
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
背景情况:
- 新生儿败血症评估涉及血液培养以指导抗生素治疗.
- 确定最佳的抗生素持续时间对于新生儿护理至关重要.
研究的目的:
- 评估怀疑败血症的新生儿血液培养阳性时间.
- 为停止抗生素治疗建立基于证据的标准.
主要方法:
- 从新生儿重症监护病房患者的血液培养数据的回顾性审查.
- 对阳性反应的时间分析,按生物体类型和败血症发病情况分层.
- 包括一个不包括潜在污染物的子分析.
主要成果:
- 血培养阳性反应的中位时间为17小时 (IQR 12-23).
- 97.9%的格拉姆阴性和93.6%的格拉姆阳性生物体在24小时和36小时内呈阳性结果.
- 所有早期发作的败血症培养 (100%) 和大多数晚期发作的败血症培养 (95.7%) 分别在24小时和36小时内产生.
结论:
- 新生儿的血液培养通常在36小时内显示阳性.
- 治疗新生儿败血症的抗生素可以在36小时内安全地停止在看起来健康的婴儿身上,特别是当没有发现感染源时.
相关概念视频
01:20Sputum Studies II: Culture and Sensitivity
226
Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
226
01:26Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture
148
Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
148
01:30Pneumonia III: Complications and Assessment
132
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
132