在第一季度子宫动脉多普勒测量中观察者间和观察者内部的可靠性
Leah I Prins1, Eric Smith2, Christiana M Naaktgeboren3
1Department of Obstetrics and Gynecology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands; Amsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands.
概括
第一个三个月子宫动脉多普勒PI测量显示中等可靠性,负面影响较高的BMI. 提高多普勒超声波和生物化学标记物的可靠性是怀孕风险评估中更好的临床实用性的关键.
科学领域:
- 产科和妇科 产科和妇科
- 医疗成像医学成像
- 生殖医学 生殖医学
背景情况:
- 对子宫动脉 (UtA) 脉动性指数 (PI) 的多普勒超声波测量对于评估怀孕风险至关重要.
- 精确的UtA PI测量有助于识别诸如子宫前和胎儿生长限制等疾病.
- 这种技术为临床决策提供了信息,例如启动低剂量阿司匹林治疗.
研究的目的:
- 评估第一季度腹腔间多普勒 UtA PI测量的观察者间和观察者内部可靠性.
- 通过使用超声技术 (TRUST) 的真实可重现性标准来评估这些测量的一致性.
- 调查探头类型和身体质量指数 (BMI) 等因素对测量可靠性的影响.
主要方法:
- 对低风险单子妊娠 (11-13周+6天妊娠期) 的前性观察性横截面研究.
- 两个超声波测试仪对每个参与者进行了顺序的横腹多普勒UtAPI测量 (右和左).
- 统计分析包括探测器类型和BMI的内部和观察者间可靠性 (ICC) 和灵敏度分析.
主要成果:
- 总共有689个UtA多普勒测量得到了58名妇女.
- 观察者内部可靠性显示了差到中度的类内相关性 (ICC) 值.
- 观察者之间的可靠性对于单个动脉来说很差,但对于平均水平来说适度;更高的BMI与ICC相反相关.
结论:
- 根据TRUST标准,第一季度的Doppler UtA PI测量显示只有中等的可靠性.
- 发现较高的母体BMI会对这些多普勒测量的可靠性产生负面影响.
- 通过研究和培训提高子宫多普勒和生物化学标记物的可靠性对于改善临床应用至关重要.
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