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Updated: Jun 15, 2025

Evaluation of Protein–Protein Interactions using an On-Membrane Digestion Technique
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对calpain-1和calpain-2蛋白酶子单元相互作用的量化和结构功能分析

Ivan Shapovalov1, Prawin Rimal2, Pitambar Poudel2

  • 1Department Pathology and Molecular Medicine, School of Medicine, Queen's University, Kingston, Ontario, Canada; Division of Cancer Biology and Genetics, Sinclair Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.

The Journal of biological chemistry
|May 18, 2025
PubMed
概括

卡尔帕因-1和卡尔帕因-2是癌症的治疗点. 研究人员开发了生物传感器来研究calpain异构化,识别了用于全抑制策略的关键残留物.

关键词:
产品环境印领域全osteric调节的调节.有约束力的自由能源.生物传感器生物传感器和是最重要的.头部疼痛 (calpain) 是一种疼痛.分化二元化是指二元化的过程.解离常数是一种解离常数.蛋白质蛋白质相互作用

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