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分子对接见解:绿色合成的氧化铁纳米颗粒与细菌蛋白的相互作用机制

Soghra Nashath Omer¹, Panchamoorthy Saravanan², Senthilnathan¹

¹School of Bio-Sciences and Technology, Vellore Institute of Technology, Vellore - 632014, Tamilnadu, India.

Microbial pathogenesis

|May 18, 2025

概括

环保的氧化铁纳米颗粒 (Fe2O3 NPs) 用Morinda citrifolia叶提取物进行了合成. 这些纳米颗粒具有显著的抗菌和抗氧化特性,具有低毒性,可用于各种应用.

科学领域:

纳米材料的绿色合成
生物医学应用程序
环境科学环境科学

背景情况:

纳米粒子为各种应用提供独特的特性.
开发环保的合成方法对于可持续性至关重要.
氧化铁纳米粒子 (Fe2O3 NPs) 在医学和环境修复方面显示出潜力.

研究的目的:

合成Fe2O3NP使用Morinda citrifolia叶提取物作为绿色的减少和稳定剂.
为了描述合成的Fe2O3NP.
评估Fe2O3NP的抗菌,抗氧化和毒理性质.

主要方法:

气色谱-质谱 (GC-MS) 用于植物化学分析.
扫描电子显微镜 (SEM),UV-Vis光谱,FTIR和XRD用于表征.
抗菌试验 (ZOI,MIC),抗氧化剂试验 (聚,DPPH) 和毒性试验 (植物毒性,细胞毒性).

主要成果:

在叶子提取物中,GC-MS确定了负责抗菌活性的生物活性化合物.
合成的Fe2O3NP表现出显著的抗菌活性,对抗阳性和阴性细菌.
观察到强烈的抗氧化活性和低的植物毒性和细胞毒性.

结论:

莫林达叶提取物对Fe2O3NP的绿色合成有效.
合成的Fe2O3NP具有有前途的抗菌和抗氧化特性.
这些Fe2O3NP显示出在医学和环境领域的可持续应用的潜力,因为它们的毒性很低.

关键词:

抗菌和生物膜研究研究.铁氧化物NP (Fe(2) O(3)) 是一种铁氧化物.分子对接分析分子对接分析

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