左主动心律失常性心肌病的分子特征和细胞组成揭示了关键路径和治疗点

Yiqi Zhao1, Mengda Xu1, Xiumeng Hua1

  • 1Beijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials, Animal Experimental Centre, Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China; Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

概括

单核RNA测序揭示了左主导心律失常性心肌病 (LACM) 中纤维细胞和脂肪细胞的增加. 这项研究确定了心肌细胞和其他细胞中的关键转录特征,为LACM病原体提供了洞察力.

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