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Marc Pawlitzki¹, Alexander Stahmann², Niklas Frahm²

¹Department of Neurology, Medical Faculty, University Hospital Düsseldorf, Düsseldorf, Germany. MarcGuenter.Pawlitzki@med.uni-duesseldorf.de.

Neurological research and practice

|May 18, 2025

概括

在德国多发性硬化症 (MS) MRI 扫描中加多 (Gd) 的使用在2021年指导方针之后显著下降. 尽管这种下降,但Gd仍然在使用,这需要进一步调查.

科学领域:

神经学神经学
放射学放射学是一门学科.
医疗成像医学成像

背景情况:

磁共振成像 (MRI) 对于多发性硬化症 (MS) 的诊断和监测至关重要.
基于加多的对比剂 (Gd) 经常用于MS MRI.
由于对Gd积累的担忧,于2021年更新了国际指导方针,建议限制使用.

研究的目的:

评估2021年关于德国MS MRI中Gd利用的国际指南的影响.
分析Gd在骨,脊柱和综合性多发性硬化症MRI扫描中的使用趋势.

主要方法:

在德国多发性硬化病登记册 (2019-2024) 中,对12833名多发性硬化病患者的MRI数据进行了回顾性分析.
用于评估Gd使用趋势的一般化添加模型随着时间的推移和MRI类型.

主要成果:

从2020年到2024年,在所有MRI类型 (头骨,脊柱,联合) 中观察到Gd使用的显著下降.
Gd的使用率从超过74%降至41%的骨,78%降至39%的脊柱,和81%降至59%的综合MRI.
在MS诊断后的前五年内,Gd使用的减少最明显.

结论:

在MS MRI中Gd的使用量大幅下降,与2021年的指导方针保持一致.
尽管下降,但Gd仍在超过三分之一的多发性硬化症MRI扫描中使用,需要进一步的研究和评估.

关键词:

基于加多的对比度是基于加多的.磁共振成像技术磁共振成像技术复发性多发性硬化症复发性多发性硬化症

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