皮和种子粉消费对抗氧化/亲氧化系统和心肌细胞收缩功能的影响
Priscila Murucci Coelho1, Luísa Martins Simmer1, Amanda Rangel Madureira2
1Postgraduate Program in Nutrition and Health, Center of Health Sciences, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
概括
在患有2型糖尿病 (T2DMOb) 的肥胖大鼠中,百合花皮和种子粉没有改变抗氧化剂水平. 然而,皮面粉改善了心脏放松,这表明T2DMOb对心血管并发症的潜在治疗益处.
科学领域:
- 心血管研究研究心血管研究
- 代谢障碍 代谢障碍 代谢障碍
- 营养科学 营养科学
背景情况:
- 2型糖尿病 (T2DM) 显著增加心血管疾病的风险,通常涉及心脏功能受损和处理.
- 在T2DM中活性氧物种 (ROS) 的增加有助于胰腺β细胞损伤和内皮功能障碍.
- 百合花皮和种子面粉含有丰富的抗氧化剂,有可能减轻T2DM (T2DMOb) 肥胖的氧化应激.
研究的目的:
- 为了研究柳皮和种子面粉对T2DM肥胖大鼠的抗氧化/亲氧化系统的影响.
- 在T2DMOb模型中评估花粉消费对心肌细胞收缩功能和处理的影响.
主要方法:
- 在17周的时间里,Wistar老鼠诱导了肥胖和T2DM.
- 患有T2DM的肥胖大鼠在5周内接受了花皮面粉或花种子面粉的治疗.
- 分析了心脏重塑,氧化应激生物标志物,心肌细胞收缩性和处理.
主要成果:
- 花粉治疗没有显著改变体重,脂肪,心脏形态或氧化应激生物标志物.
- 虽然李奇治疗没有影响分数缩短,但李奇皮面粉减少了心肌放松时间.
- 百合花种子面粉降低了腹筋水平,但没有改善放松时间或衰变.
结论:
- 在T2DMOb模型中,百合花皮和种子粉没有显示出显著的抗氧化作用.
- 百合花皮面粉对心肌放松时间产生有益影响,这表明T2DMOb.有改善心脏功能的潜力.
- 进一步的研究可能会探索皮粉对T2DM心脏功能的影响的具体机制.
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