13. 13. 13. 一个人的生活. 三叉子神经疼痛 三叉子神经疼痛
Bart Jorrit Snel1, Steven P Cohen2,3, Serdar Erdine4
1Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
概括
三神经疼痛 (TN) 的诊断依赖于患者病史和MRI. 治疗包括卡巴马西平等药物,或微血管解压 (MVD) 和射频切除等程序.
科学领域:
- 神经学 神经学
- 疼痛管理 疼痛管理
- 神经外科 神经外科
背景情况:
- 三神经疼痛 (TN) 是一种使人虚弱的疾病,导致严重的面部疼痛.
- 它的特点是三角神经分布中的短暂的,类似电击的疼痛.
- 疼痛是由无害的刺激触发的,显著影响生活质量.
研究的目的:
- 审查和总结有关三角神经疼痛诊断和治疗的当前文献.
- 提供诊断标准和治疗选择的概述.
- 为TN患者的临床决策提供信息.
主要方法:
- 关于三角神经疼痛诊断和治疗的综合文献搜索.
- 综合有关诊断方法和治疗干预措施的发现.
- 审查支持不同治疗方式的证据.
主要成果:
- 诊断主要基于患者病史;神经学检查在经典TN中通常是正常的.
- 建议用于成像的磁共振成像 (MRI) 与对比度.
- 第一线医疗治疗包括碳二或氧二.
- 适合候选人的微血管减压 (MVD) 是首选的.
- 穿皮手术,如射频热凝等是可选的,特别是对于老年人或并发症患者.
结论:
- 目前对TN治疗的建议是基于低质量的证据.
- 微血管减压 (MVD) 和射频剥离是首选的侵入性治疗方法.
- 需要进一步进行高质量的研究,以澄清各种干预措施的风险效益比率.
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