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在噪音引起的听力损失患者中异常的静态和动态功能网络连接

Ranran Huang¹, Aijie Wang¹, Yunxin Li¹

¹Department of Radiology, Yantaishan Hospital, Yantai, China.

Quantitative imaging in medicine and surgery

|May 19, 2025

概括

噪音引起的听力损失 (NIHL) 改变了大脑的连接,影响了注意力和执行网络. 这些变化与焦虑和耳的严重程度相关,为NIHL提供了洞察力.

科学领域:

神经科学是一个神经科学.
听力学听力学是指听力学.
医疗成像医学成像

背景情况:

噪音引起的听力损失 (NIHL) 与皮质可塑性变化有关.
之前的研究探讨了听力丧失对大脑的影响.
这项研究研究了NIHL患者的功能连接.

研究的目的:

在NIHL中检查静态功能网络连接 (sFNC) 和动态功能网络连接 (dFNC).
使用独立组件分析 (ICA) 识别与NIHL相关的大脑网络变化.
为了将功能连接性变化与NIHL的临床特征相关联.

主要方法:

招募了69名NIHL患者和57名健康对照 (HC).
用MMSE,HAMA和THI评估参与者.
获取的3D-T1WIFSPGR和静态fMRI数据用于基于ICA的sFNC和dFNC分析.

主要成果:

在NIHL患者中,腹部注意网络 (VAN) 和执行控制网络 (ECN) 之间的sFNC增加.
在NIHL患者的特定大脑状态中观察到VAN和ECN之间的dFNC增加.
异常的sFNC和dFNC与焦虑 (HAMA) 和耳 (THI) 严重程度正相关.

结论:

噪音暴露导致的听力损伤会改变大脑功能.
在sFNC和dFNC中,NIHL表现出明显和共同的异常.
结合的sFNC和dFNC分析可以提高对NIHL神经机制的理解.

关键词:

噪音引起的听力损失 (NIHL)动态功能网络连接能力 (dFNC)噪音暴露时间静止状态功能磁共振成像 (RS-fMRI) 进行.静态功能网络连接 (sFNC) 系统

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相关概念视频

Hearing

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.