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在2名患有乳腺瘤的患者中,脱水素二二酸盐水平升高:一个未被认可的关联
Joseph Arguinchona1, Aditi Kumar1, Divya Yogi-Morren2
1Department of Endocrinology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
JCEM case reports
|May 19, 2025
概括
过多的益生菌素的状况 - - 过多的益生菌素 - - 过高的益生菌素血清,可以与高水平的脱氨固醇硫酸盐 (DHEA-S) 相关联. 在两名男性患者中,用卡伯戈林治疗潜在的乳腺瘤使DHEA-S正常化.
科学领域:
- 内分泌学 在内分泌学.
- 生殖内分泌学 生殖内分泌学
- 神经内分泌学神经内分泌学
背景情况:
- 上腺的雄激素产生主要由ACTH调节.
- 在高血和升高的硫酸脱氨 (DHEA-S) 之间存在较少的相关性.
研究的目的:
- 描述两个案例,说明高血和升高的DHEA-S之间未被认可的联系.
- 突出前乳腺瘤在引起DHEA-S升高的潜在作用.
主要方法:
- 两名男性患者的病例报告显示DHEA-S和益生菌素水平升高.
- 诊断工作包括成像 (CT,MRI) 和生物化学测试.
- 用卡贝戈林治疗和监测激素水平.
主要成果:
- 这两位患者的DHEA-S和益生菌素水平都升高.
- pituitary macroadenoma 在这两种情况下都被确定为病因.
- 卡伯戈林治疗导致了前素和DHEA-S水平的正常化.
结论:
- 由于益生菌瘤而导致的超级益生菌血症是升高DHEA-S的不常见原因.
- 在排除其他病因后,在患有高DHEA-S的患者中应考虑这种关联.
- 治疗益生菌瘤的医学治疗可以有效地使DHEA-S水平正常化.
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