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Updated: May 21, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
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跨SMN2的全面分析排除了DNA甲基化作为脊髓肌肉缩的表观遗传生物标志物

Maria M Zwartkruis1,2, Joris V Kortooms1, Demi Gommers1,2

  • 1Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands.

iScience
|May 19, 2025
PubMed
概括

脊椎肌肉缩 (SMA) 研究发现,血液中的SMN2基因甲基化不能预测疾病的严重程度或治疗反应. 然而,特定的SMN2区域的与年龄相关的甲基化变化表明它在发育和衰老中起作用.

关键词:
卫生科学 卫生科学内部医学 内部医学医学专业 医学专业医学 医学 医学 医学 医学神经学 神经学

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