在患有慢性病的成年人中,根据性别对心血管风险概况的差异:基于NHANES的分析
Hannah T Belikoff1, Ramya Walsan2, Cara M Hildreth1
1Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia.
患有慢性病 (CKD) 的女性与男性有不同的心血管风险因素,包括糖尿病和高血压的几率较低,但腰围增加的几率更高. 了解这些基于性别的差异对于个性化CKD护理至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 是慢性病 (CKD) 患者的主要死亡原因.
- 共同的风险因素导致CKD患者心血管疾病风险增加.
- 这些风险因素的性别特异性需要进一步研究.
研究的目的:
- 研究CKD患者心血管风险因素的性别差异.
- 了解性如何影响心血管风险在功能下降的背景下.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) (2007-2018) 的数据.
- 根据专蛋白与肌素的比率或估计的淋巴细胞过率 (eGFR) 来分类CKD.
- 使用双向ANOVA和多变量逻辑回归来分析性别特异性心血管风险因素.
主要成果:
- 两性功能下降与缩血压升高和血红蛋白/血红素降低相关.
- 与男性相比,患有CKD的女性患糖尿病,高血压,低血红素和高甘油的几率较低.
- 患有CKD的女性比男性更有可能增加腰围和低高密度脂蛋白胆固醇 (HDL-C).
结论:
- 在患有CKD的个体中,心血管风险因素存在显著的基于性别的差异.
- 与男性相比,患有CKD的女性具有明显的风险因素概况.
- 在CKD研究和管理中纳入性别特异性方法对于个性化患者护理至关重要.
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