系统性硬化症患者手和手腕关节的超声波评估
Zeynep Ermancık1, Müçteba Enes Yayla2, Ahmet İlbay2
1Department of Internal Medicine, Faculty of Medicine, Ankara University, Ankara, Turkey.
Journal of scleroderma and related disorders
|May 19, 2025
概括
系统性硬化症 (SSc) 患者经常表现出异常的肌肉骨超声检查结果,包括肌炎和肌炎,特别是在手腕. 年龄较大的SSc患者患有突炎,可能有炎症标志物升高.
科学领域:
- 类风湿病学 类风湿病学
- 肌肉骨成像系统的成像
- 系统性自身免疫性疾病
背景情况:
- 系统性硬化症 (SSc) 是一种复杂的自身免疫性疾病,其特征是皮肤和内部器官纤维化.
- 肌肉骨表现,包括关节炎,在SSc中很常见,但它们的超声波 (US) 特性需要进一步阐明.
研究的目的:
- 在SSc患者的手和手腕中识别异常的肌肉骨US发现,与健康对照者相比.
- 在SSc患者中评估突炎和突炎的严重程度.
- 为了将美国的发现与人口,临床和血清学特征相关联.
主要方法:
- 一项涉及50名SSc患者和50名健康对照者的横截面研究.
- 肌肉骨美国对元手腕关节 (MCP),近端关节 (PIP),远端关节 (DIP) 和手腕关节的评估.
- 美国发现和SSc患者和对照者之间的临床/血清学数据的比较,以及SSc患者与无突炎之间的比较.
主要成果:
- 与对照组相比,SSc患者表现出明显更高的肌炎,肌性缩,肌性炎和肌性炎的频率 (p < .001对于肌炎,肌性炎,肌性炎).
- 在SSc患者中,轻度综合炎和紧张综合炎更为普遍,而中度至重度炎症的频率相似.
- 手腕是受影响最常见的关节. 综合炎患者年龄较大,红细胞沉积率 (ESR) 和C反应蛋白 (CRP) 水平较高.
结论:
- 肌肉骨US揭示了SSc患者常见的异常,如肌炎,肌炎和肌过敏,无论关节痛.
- 高龄和急性相反应物 (ESR,CRP) 的升高与SSc患者的突炎有关.
- 美国是检测和描述SSc.联合参与的有价值的工具.
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