皮革剃须废物提取物作为在笔石墨电极上的电化学修饰剂,用于药品中对白醇的确定
Wael Bosnali1, Şeyma Korkmaz1, Ayşen Demir Mülazımoğlu2
1Institute of Science, Chemistry Department, Necmettin Erbakan University, Konya 42090, Türkiye.
ACS omega
|May 19, 2025
概括
一种新的方法使用皮革剃须废物提取物 (LSWE) 来修改笔石墨电极 (PGE) 以检测敏感的偏醇 (PAR). 这种可持续的方法提供了准确的药物分析与最小的干扰.
科学领域:
- 电分析化学 电分析化学
- 材料科学 材料科学 材料科学
- 环境化学环境化学
背景情况:
- 开发具有成本效益和灵敏的电化学传感器用于制药分析至关重要.
- 利用废物材料制造功能性纳米材料提供了可持续的解决方案.
- 皮革剃须废弃物 (LSW) 是新型电极修饰剂的潜在来源.
研究的目的:
- 开发一种简单,方便和灵敏的方法来测定类醇 (PAR).
- 为此目的使用皮革剃须废物提取物 (LSWE) 改性笔石墨电极 (PGE).
- 为了验证在真实药品样本中分析PAR的方法.
主要方法:
- 皮革剃须废物用乙尼来提取,以获得LSWE.
- 笔石墨电极 (PGE) 通过循环电压计用LSWE (0.1LSWE/PGE) 进行了修改.
- 平方波吸附剥离电压测量 (SW-AdSV) 用于对的量化.
主要成果:
- 对于5-100μM之间的PAR度建立了线性关系 (r2 = 0.997).
- 修改后的电极表现出高灵敏度 (196.46 μA μM−1 cm−2) 与低检测极限 (1.6 μM).
- 传感器表现出极好的选择性,常见的生物和离子物种的干扰是可以忽略不计的.
结论:
- 经LSWE修改的PGE是一种高度有效的传感器,用于敏感和选择性检测.
- 该方法对制药配方中的青精确分析具有很大的前景.
- 这项研究突出了将工业废物用于先进的电化学应用的潜在用途.
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