甲状腺功能障碍在COPD中的患病率和临床表征:系统性审查和元分析
Ling Wu1, Li He1, Xiaorong Hu1
1Department of Respiratory and Critical Care Medicine, The First People's Hospital of Shuangliu District, Chengdu, Sichuan, China.
甲状腺功能障碍影响超过40%的慢性阻塞性肺病 (COPD) 患者,最常见的是非甲状腺疾病综合征. 早期查和关注临床特征对于治疗甲状腺问题COPD患者至关重要.
科学领域:
- 肺部医学 肺部医学
- 内分泌学 在内分泌学.
- 系统性审查和元分析
背景情况:
- 慢性阻塞性肺病 (COPD) 的患病率正在上升,并发症和器官功能障碍的增加.
- 甲状腺功能障碍是COPD患者常见的并发症,需要为临床实践提供最新的证据.
- 以前的系统审查需要补充,以指导COPD和甲状腺功能障碍管理的最佳实践.
研究的目的:
- 为了确定COPD患者甲状腺功能障碍的整体患病率.
- 为了确定COPD患者中最常见的甲状腺功能障碍类型.
- 为了比较稳定和恶化的COPD与甲状腺功能障碍之间的临床特征和患病率.
主要方法:
- 在EMBASE,Web of Science,Cochrane和PubMed进行了系统的文献搜索,寻找关于COPD和甲状腺功能障碍的研究.
- 资格选,数据提取和质量评估由两个审查员独立进行.
- 使用元分析和回归分析来确定患病率,探索异质性,并比较临床特征.
主要成果:
- 包括12项研究,显示甲状腺功能障碍在COPD的总体患病率为42.1%.
- 非甲状腺疾病综合征 (NTIS) 是最常见的类型,发生在45.3%的病例中.
- 与没有甲状腺功能障碍的COPD患者相比,COPD患者的PCO2和白蛋白水平较低,FEV1%较高.
结论:
- 甲状腺功能障碍在COPD中非常普遍,NTIS是最常见的形式.
- 甲状腺功能障碍可能会影响COPD肺功能,导致白蛋白水平降低.
- 查COPD患者的甲状腺功能和识别相关的临床特征对于改善管理至关重要.
更多相关视频
04:03Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD
Published on: September 27, 2024
04:53Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
相关概念视频
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
COPD: Management Using Bronchodilators and Corticosteroids
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
