非结核性菌根脉瘤的临床特征和结果
Hitoshi Suzuki1, Daisuke Ito1, Mari Shinoda1
1Department of Thoracic Surgery, Mie Prefectural General Medical Center, Yokkaichi, JPN.
Cureus
|May 19, 2025
概括
非结核性菌根性 (NTM) 瘤是一种罕见的疾病,预后比其他类型的瘤更差. 早期的手术干预对于状NTM瘤至关重要,以改善结果.
科学领域:
- 肺部医学 肺部医学
- 传染性疾病 传染性疾病
- 胸部外科手术 胸部外科手术
背景情况:
- 非结核菌 (NTM) 感染正在增加.
- 肺NTM瘤是一种罕见但严重的肺NTM疾病并发症.
研究的目的:
- 为了阐明NTM empyema的临床特征和结果.
- 为了比较NTM empyema与其他形式的empyema和没有 empyema的NTM疾病.
主要方法:
- 从2012年1月到2024年12月的医疗记录的回顾性审查.
- 包括患有NTM瘤的患者,没有瘤的NTM疾病和其他瘤原因.
- 定义NTM empyema是从流和性液体的多叶膜输液中得到的阳性NTM培养物.
主要成果:
- 在NTM empyema患者中,年龄较大,男性更频繁,查尔森并发症指数 (CCI) 更高,并且更经常出现纤维腔疾病.
- 与没有 empyema 的 NTM 疾病相比,NTM empyema 的长期预后较差.
- 肺胸部发病率较高的NTM (66.7%) 与其他 (14.8%).
- 状NTM肺瘤的死亡率明显高 (40.0%),高于其他状肺瘤 (11.5%).
结论:
- NTM 瘤与特定的人口和临床因素有关,包括纤维腔疾病和并发病的更高患病率.
- NTM带有不良预后,并且在没有干预措施 (如胸管排水或手术) 治疗时具有挑战性.
- 建议在患有状NTM empyema的患者进行早期手术干预.
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