自发性出血性胆囊破裂在原发性硬化胆管炎的背景下引起冲击
Evangelia Florou1, Shirin Ubaid1, Matthew Seager2
1Hepato-Pancreato-Biliary Surgery, King's College Hospital, London, GBR.
Cureus
|May 19, 2025
概括
造成冲击的出血性胆囊破裂是罕见的,特别是在年轻患者中. 这一案例突出了一个患有原发性硬化性胆管炎的患者的独特案例,强调了潜在的罕见并发症.
科学领域:
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
- 手术并发症 手术并发症
背景情况:
- 初级硬化性胆道炎 (PSC) 是一种自身免疫性肝病 (AiLD).
- 胆囊出血 (HG) 是急性胆囊炎的罕见并发症,通常见于老年人,服用抗凝药的患者.
- 胆囊破裂导致出血性休克是一个极其罕见的事件.
研究的目的:
- 报告第一个导致胆囊破裂的胆囊破裂病例,该病例发生在一个患有肝硬化PSC的年轻患者身上,导致出血性休克.
- 为了突出艾尔迪患者常见病理的罕见并发症.
主要方法:
- 一个29岁的女性患有PSC和脏动脉动脉瘤的案例介绍.
- 诊断工作包括生物化学和计算机断层扫描 (CT) 扫描.
- 管理涉及紧急腹腔切除术以切除胆囊和控制出血.
主要成果:
- 扫描显示了胆囊破裂,有活跃的出血和血.
- 患者呈现出血动力学不稳定性和高胆红素水平.
- 成功的手术切除和没有术后并发症的恢复.
结论:
- 导致血液动力学休克的出血性胆囊破裂是一个极其罕见的事件.
- 该病例代表了PSC患者中首次报告的由于HG引起的内部出血.
- 临床医生应该意识到PSC患者的罕见并发症,并且AiLD和出血之间的关系需要进一步调查.
相关概念视频
Chronic Bowel Disorders: Introduction
374
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
374
Esophageal Varices-II: Clinical Features and Management
32
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
32
Inflammatory Bowel Disease I: Ulcerative Colitis
103
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
103
Esophageal Varices-I: Introduction
53
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
53
Esophageal Perforation-I: Introduction
54
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
54


