,肥胖或两者兼而有之. 皮肥胖相关风险的主要变量是什么?
Alejandro Álvarez-Bustos1,2, Jose A Carnicero1,3, Walter Sepúlveda-Loyola4
1Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.
Innovation in aging
|May 19, 2025
概括
麻症和肥胖症在老年人中增加了脆弱风险,而麻症是主要的驱动因素. 这项研究阐明了萨尔科佩尼亚和肥胖在不良结果中的不同作用.
科学领域:
- 老年学是一门学科.
- 老年病的医生 老年病的医生
- 公共卫生 公共卫生
背景情况:
- 麻性肥胖 (SO),肥胖和麻症与老年人的不良结果有关.
- 这些条件对风险的独立和综合贡献需要澄清.
研究的目的:
- 评估型肥胖症,肥胖症及其相互作用在与型肥胖症相关的风险中的作用,特别是脆弱性,残疾和死亡率.
主要方法:
- 利用了来自托莱多健康衰老研究 (TSHA) 的数据,该研究是一组65岁以上的社区成年人.
- 在基线评估肥胖 (BMI ≥30) 和皮症 (FNIH标准);评估脆弱性 (FP,FTS5) 和残疾 (Katz指数) 横截面和纵向.
- 使用后勤和考克斯回归模型来确定与不良事件的关联.
主要成果:
- 在截面上,SO,sarcopenia和肥胖与虚弱和残疾有关.
- 从长度上看,sarcopenia独立预测了所有不良事件 (虚弱,残疾,死亡率).
- 肥胖症和肥胖症与事件脆弱性有关,但与残疾或死亡率无关. 萨科佩尼亚增加了对脆弱性肥胖的风险,但没有发现显著的相互作用.
结论:
- 皮症和肥胖症在皮性肥胖症中增加了虚弱的风险,而不是增加的风险.
- 萨科佩尼亚是导致萨科佩尼亚肥胖症不良结果风险增加的主要因素.
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