低酸血症:揭示了重症病患COVID-19患者的ICU死亡率与致命连接:一个多中心观察性研究
Şahin Temel1, Pervin Hanci2, Akbudak Ismail Hakkı3
1Erciyes University, School of Medicine, Department of Internal Medicine, Division of Intensive Care Medicine, Kayseri, Turkey.
Journal of medical biochemistry
|May 19, 2025
概括
低酸血症是重症COVID-19患者常见的疾病,与更糟糕的结果有关. 监测血清水平对于改善这些患者的护理和降低死亡率至关重要.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 腎科/泌尿科 腎科/泌尿科
背景情况:
- 低酸盐血症与各种患者群体的不良结果有关.
- 有限的数据存在于临界病的COVID-19患者的低酸血症的流行率和影响.
研究的目的:
- 为了确定COVID-19危急病患者中低酸血症的频率.
- 调查血清含量与临床结果之间的相关性.
主要方法:
- 对205名确诊COVID-19患者的RT-PCR进行了回顾性观察性研究.
- 包括患有呼吸衰竭的患者,需要接受ICU治疗>24小时.
- 分析了临床参数,并发症,呼吸辅助和血清水平.
主要成果:
- 25%的患者在ICU的前三天内出现了低血症 (的中位数为1.02 mmol/L).
- 低酸血症与显著更长的ICU停留有关 (p=0.046).
- 第三天水平独立预测了ICU死亡率 (HR=1.48,p=0.006).
结论:
- 低酸盐血症影响了严重病情严重的COVID-19患者的很大一部分.
- 这种情况与 ICU 死亡率的增加和 ICU 停留时间的延长有关.
- 对于重症COVID-19患者,建议定期监测血清的水平.
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