在1型和2型糖尿病患者中,SARS-CoV-2疾病的严重程度
Anthony Shadiack1, Alexis White1, Prasad Munusamy1
1Grand Strand Medical Center, Myrtle Beach, South Carolina.
HCA healthcare journal of medicine
|May 19, 2025
概括
患有1型 (T1D) 和2型 (T2D) 糖尿病患者的疾病严重程度和COVID-19死亡率增加. 与T1D患者相比,T2D患者的治疗结果更差,住院时间更长.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 糖尿病是一种已知的严重COVID-19的风险因素.
- 在SARS-CoV-2患者中,只有有限的数据可以比较1型糖尿病 (T1D) 和2型糖尿病 (T2D) 之间的疾病严重程度.
研究的目的:
- 为了比较T1D和T2D患者之间的COVID-19疾病的严重程度.
- 为了确定结果的差异,如通风,ICU入院,死亡率和停留时间.
主要方法:
- 从2020年3月到2020年11月的COVID-19患者记录的回顾性审查.
- 对76,467名COVID-19患者的分析,包括那些没有糖尿病 (NON),T2D和T1D的人.
- 后勤回归用于评估疾病严重程度和结果的预测因素.
主要成果:
- 与非T1D患者相比,T1D和T2D患者需要通风,ICU入院和死亡率都显著增加.
- T1D患者的ICU入院几率是5.68倍,而T2D患者的入院几率是1.82倍.
- 与A1C水平相似的T1D患者相比,A1C>7%或>8%的T2D患者的通风率增加,住院时间更长.
结论:
- T1D和T2D是SARS-CoV-2疾病严重程度增加的独立预测因素.
- 较老的T2D患者表现出比T1D患者更糟糕的结局和更长的住院时间.
- 糖尿病类型影响COVID-19的严重程度和患者的结果.
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