通过使用Fmoc固相合成 (SPPS) 策略合成二氧化酸:一种商业上可行的方法

Kiran Aluri1,2, Srinivas Basavoju2, Jagadeesh B Rangisetty1

  • 1Biophore India Pharmaceuticals Private Limited, Hyderabad, Telangana, India.

概括

在cetrorelix合成期间最大限度地减少种族化是至关重要的. 使用特定的合剂和添加剂在固相合成中降低了L-氨酸和L-氨酸的种族化到0.5%以下.

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