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Updated: May 22, 2025

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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Published on: June 26, 2020

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PRDX1保护ATM免受酸盐诱导的蛋白毒性,并在DNA损伤信号过程中保持其稳定性

Reem Ali1, Mashael Algethami2, Amera Sheha2

  • 1College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.

Oncotarget
|May 19, 2025
PubMed
概括

氧化素1 (PRDX1) 稳定了ATM激酶,这对DNA修复至关重要. 失去PRDX1会增加对化疗的敏感性,这表明PRDX1是治疗反应的预测因子和潜在的治疗标.

关键词:
细胞循环中的细胞循环.同类的重组组合.蛋白质相互作用 蛋白质相互作用蛋白质修饰是一种蛋白质修饰.氧化还原信号传递.

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