在两个旧金山医院的COVID-19封锁期间,早产和低出生体重出生率的变化
Anoushka Kathiravan1, Zoe R Schauer1, Janet M Wojcicki2,3
1Pediatric Gastroenterology, Hepatology and Nutrition, University of California, San Francisco, CA, USA.
Journal of epidemiology and global health
|May 19, 2025
概括
与2019年相比,旧金山的COVID-19封锁显著降低了早产率,并在2020年8月至12月期间增加了妊娠时间. 这些发现表明,严格的家居措施可能对怀孕结果产生了积极的影响.
科学领域:
- 孕产妇和胎儿的医学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 随着COVID-19大流行和相关的封锁,影响了医疗保健的获取和社会压力.
- 关于疫情封锁和早产率的先前研究显示,全球的结果各不相同.
- 评估COVID-19封锁对旧金山出生结果的具体影响至关重要.
研究的目的:
- 评估COVID-19封锁对旧金山早产和低出生体重率的影响.
- 为了比较封锁期间的出生结果 (2020年3月至5月和8月至12月) 与前一年 (2019年) 的相同时期.
主要方法:
- 使用了比较性研究设计,分析了来自旧金山两个医院 (安全网和学术医疗中心) 的数据.
- 2019年和2020年间,早产 (<37周) 和低出生体重 (<2500克) 的比率进行了比较.
- 经过对混因素进行调整的后勤和线性回归模型被用于评估风险和关联.
主要成果:
- 从2020年8月到12月,早产率大幅下降 (13.20%至7.96%,p<0.01).
- 低出生体重率也出现了下降 (11.33%到9.70%,p=0.13).
- 封闭期 (八月至十二月) 保护了早产 (OR 0.65),并与更长的妊娠期和更大的出生体重相关.
结论:
- 与2019年相比,旧金山的COVID-19封锁与2020年8月至12月的早产率降低和妊娠持续时间增加有关.
- 旧金山的严格封锁措施可能有助于这些积极的分娩结果,可能是通过减少母亲的压力.
- 这项研究强调了严格的公共卫生干预措施在流行病期间对围产期健康的潜在好处.
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