养老院居民的临床药物护理作为药物相关问题识别的基石
Milada Halačová1,2,3, Marie Mieresová1,2, Dalibor Černý1,4
1Department of Clinical Pharmacy, Na Homolce Hospital, Prague, Czech Republic.
Clinical and translational science
|May 19, 2025
概括
这项研究发现,93.3%的捷克养老院居民遇到与药物相关的问题 (DRPs),通常是由于多药. 临床药剂师对于改善这种人群中的药物安全至关重要.
科学领域:
- 老年医学 老年医学
- 临床药房 临床药房
- 药物经济学 药物经济学
背景情况:
- 理性处方在老年医学是一个重要的伦理和社会经济问题.
- 多药在养老院居民中很普遍,增加了药物不良事件的风险.
- 临床药剂师在优化老年人药物治疗中的作用需要进一步调查.
研究的目的:
- 分析捷克养老院居民的与毒品有关的问题 (DRP).
- 提高公众对临床药剂师在社会护理环境中的潜在贡献的认识.
- 在这个脆弱人群中确定与DRP相关的因素.
主要方法:
- 一项多中心观察性研究,涉及捷克共和国16个养老院800名居民.
- 数据收集包括患者人口统计,药物使用和DRP的识别.
- 进行了统计分析,以确定DRP的流行率和类型以及相关的风险因素.
主要成果:
- 观察到DRP的高患病率,影响93.3%的参与者,平均每位患者有2.8个DRP.
- 最常见的DRP包括过度治疗 (19.5%),治疗不足 (12.8%),不适当的剂量 (10.6%) 和不良反应 (10.3%).
- 多药性,特别是使用七种或更多药物,与DRP风险增加密切相关 (AUC 0.842). 二类药物,PPI和NSAID经常受到影响.
结论:
- "SENIOR"项目强调了捷克养老院居民中过度多药和相关的DRP的高率.
- 临床药剂师在提高长期护理机构的老年人药物治疗的安全性和有效性方面发挥着至关重要的作用.
- 旨在优化药物管理的干预措施对于降低老年人群中DRP负担至关重要.
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