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在食大麻叶的牛肉牛的组织中,大麻素的转移和保留

Greyson Fruge¹, Geraldine Magnin², Russell Jessup³

¹Department of Agricultural Sciences, Texas State University, San Marcos, TX, USA.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment

|May 19, 2025

概括

麻叶可以给牛肉牛,但像CBD和THC这样的大麻素会在他们的组织中积累数周. 需要进行进一步的研究,以确定麻在动物料中的安全大麻素水平和禁用时间.

科学领域:

农业科学农业科学
动物营养动物营养
食品安全食品安全

背景情况:

大麻 (Cannabis sativa L.) 已被批准用于美国生产,其叶子显示出作为反动物牲畜料的潜力.
大麻中的大麻素可以积聚在动物组织中并转移到人类消费者身上,这引发了食品安全问题.
了解牲畜中的大麻素的药理动力学对于将大麻安全地纳入动物料系统至关重要.

研究的目的:

量化食用大麻叶的牛肉牛中大麻素的存在和积累.
为了确定大麻素在各种生物基质中的存在时间,包括液,血,脂肪组织和便.
为未来的研究提供安全的大麻素水平和麻养殖牲畜的禁食期的信息.

主要方法:

两个养期 (每期14天),然后是45天的监测期.
在第二阶段,五只经过小吃管的牛被草养,补充了大麻叶3.9毫克/公斤的BW CBDA混合与子立方体.
大麻素水平 (CBD, Δ9-THC) 在反液,血,脂肪组织和便中被测量在多个时间点.

主要成果:

大麻的消费导致了牛肉牛中大量的大麻素积累.
在消费后至少96小时内,在血中检测到大麻素.
脂肪组织显示大麻素积累时间长,持续至少6周.

结论:

大麻的消费导致肉牛中的大麻素积累时间延长.
血液和脂肪组织中大麻素的大量存在表明,在大麻被广泛用于牲畜料之前,需要仔细考虑.
需要进一步的研究来确定安全的大麻素积累极限,并为食大麻的动物建立适当的禁食时间.

关键词:

牛肉类牛的牛肉类牛.大麻sativa是一种大麻.大麻素是一种大麻素.食品安全食品安全大麻是一种麻.

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