通过数字和常规技术制造的后部皇冠中使用的树脂材料的单体释放:一个体外研究
The International journal of prosthodontics
|May 19, 2025
概括
这项研究比较了从五种后部修复材料中释放的单体. 虽然随着时间的推移释放量增加,但所有材料仍低于临床上可接受的极限,Cerasmart显示出最低的释放量和最高的释放量.
科学领域:
- 牙科材料科学 牙科材料科学
- 聚合物化学 聚合物化学
背景情况:
- 基于树脂的后部修复材料在牙科中被广泛使用.
- 有关这些材料可能释放的残留单体,如Bisphenol A (BPA),TEGDMA,HEMA,UDMA和Bis-GMA存在担忧.
- 了解单体化对于评估生物相容性和长期临床性能至关重要.
研究的目的:
- 量化评估和比较五种主要单体 (BPA,TEGDMA,HEMA,UDMA,Bis-GMA) 从五种不同的树脂基后部修复材料的释放.
- 在三个不同的时间点评估单体释放动力学: 1 小时,3 天,1 月.
- 为了确定单体释放水平是否超过临床上可接受的范围.
主要方法:
- 测试了五种基于树脂的材料 (Cerasmart,Gradia-Plus间接,G-ænial后部,Formlabs 3D-永久皇冠,SonicFill-3),并进行了测试.
- 准备了90个标本 (8x8x2毫米) 并浸入75%的乙醇 / 25%的水溶液中.
- 在1小时,3天和1个月后,使用高性能液体染色学 (HPLC) 分析了化剂中的单体度.
- 统计分析包括重复测量ANOVA和邦费罗尼后期测试.
主要成果:
- 所有材料,除了BPA从Formlabs 3D-永久皇冠释放,显示单体释放随着时间的推移显著增加 (P < .001).
- 塞拉斯马特始终表现出最低的整体单体释放量,而G-ænial Posterior显示出最高的.
- 格拉迪亚-Plus间接释放的BPA,TEGDMA和Bis-GMA含量最高,而G-ænial Posterior释放的UDMA和HEMA含量最高 (P < .001).
结论:
- 观察到的最高单体释放量是在一个月后从G-ænial Posterior中释放的0.8%UDMA.
- 尽管材料和时间点之间存在差异,但所有单体释放水平仍然远低于1.5% - 5%的确定的临床可接受范围.
- 材料选择和理解化概况对于后部树脂复合材料的临床应用很重要.
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