框架,以确定从平台技术创造价值的创新来源
Charles H Jones1, Marie Beitelshees2, Andrew Hill2
1Pfizer, mRNA Commercial Strategy & Innovation, New York, NY 10018.
概括
制药平台技术需要超越单一资产的新估值模型. 本研究引入了一个框架,评估药物开发中平台技术的战略,技术和适应性价值驱动因素.
科学领域:
- 制药科学 制药科学
- 生物技术是生物技术.
- 卫生经济学 卫生经济学
背景情况:
- 平台技术正在彻底改变制药研发和药物开发.
- 现有的估值模型,专注于单个资产,不充分评估平台技术价值.
- 需要一种新的方法来捕捉这些技术产生的多方面的价值.
研究的目的:
- 为评估平台技术在药品中的创新价值提供一个全面的框架.
- 开发一个结构化的方法,在整个药物开发生命周期中获取多样化的好处.
- 为研发投资和投资组合管理的战略决策提供信息.
主要方法:
- 系统的文献审查.
- 对领先的平台技术进行深入的案例研究.
- 在战略,技术和适应领域 (PVISTA) 框架中开发平台价值识别.
主要成果:
- 平台技术在战略,技术和适应性方面创造价值.
- 该PVISTA框架定义了关键的价值驱动因素和定量评估指标.
- 案例研究 (Alnylam,Genentech,Moderna) 证明了该框架的实用性和影响潜力.
结论:
- 对于平台技术来说,一个多方面的,数据驱动的估值方法是必不可少的.
- 该PVISTA框架帮助利益相关者评估长期价值和竞争优势.
- 采用这种框架可以加快转型疗法的发展.
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