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Updated: May 21, 2025

Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System.
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Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System.

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通过AB5亚基酶细胞毒素诱导ISR,通过STING激活驱动pDCs中的I型IFN表达

Daniela Barros1,2, Beatriz H Ferreira1,3, Paulina Garcia-Gonzalez2

  • 1Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Aveiro 3810-193, Portugal.

Proceedings of the National Academy of Sciences of the United States of America
|May 19, 2025
PubMed
概括

细菌细胞毒素SubAB触发了免疫细胞中展开的蛋白质反应 (UPR) 和炎症. 它特别通过STING激活在血细胞树突细胞中增强I型干扰素的产生.

关键词:
这是先天免疫力.在pDCDC中,pDC是亚化细胞毒素是什么展开的蛋白质应激反应应激反应

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