第一次后的复发率和死亡率:来自法国国家卫生数据系统的回顾性全国性研究
Quentin Calonge1,2,3, Octave Guinebretiere4, Thomas Nedelec4
1Sorbonne Université, Paris Brain Institute-Institut du Cerveau, ICM, INSERM, CNRS, Pitié-Salpêtrière Hospital, France.
Neurology
|May 19, 2025
概括
状态 (SE) 携带高风险的复发和死亡在三年内. 识别风险因素,如年龄较小,先前的和并发症,可以改善患者在SE后的随访.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 状态 (SE) 的短期死亡率很高,但长期的结果不太清楚.
- 关于SE复发率和长期死亡率的数据有限.
研究的目的:
- 为了确定第一次SE事件后的3年复发率和死亡率.
- 确定与SE复发和死亡率相关的风险因素.
主要方法:
- 使用法国国家卫生数据系统 (2011-2016) 进行的回顾性队列研究.
- 包括成人和婴儿患者在首次SE住院后幸存下来.
- 随访3年,使用考克斯模型分析复发,死亡率和死亡原因.
主要成果:
- 3年SE复发率为16.7%,死亡率为25%.
- 与复发相关的因素包括年龄较小,先前,酒精使用和并发症.
- 男性性别和年龄较大与死亡率有关,而渐进性原因和并发症与两者有关.
结论:
- 在SE事件发生后3年内,存在SE复发和死亡的重大风险.
- 确定了许多不可修改的风险因素,可以帮助规划患者的随访.
- 进一步了解这些因素对于优化SE后护理至关重要.
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