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SOFA评分,APACHE II评分和WBC计数的价值,用于评估败血症患者的死亡风险:一项回顾性研究

Dengkai Li¹, Yanfang Wei², Chunfang Zhang¹

¹Department of Intensive Care Unit, Aviation General Hospital, Beijing, China.

|May 19, 2025

概括

早期的败血症预后至关重要. 序列器官衰竭评估 (SOFA) 评分,APACHE II 评分和白细胞 (WBC) 计数有效预测败血症患者的死亡风险,特别是当它们结合在一起时.

科学领域:

关键护理医学关键护理医学
传染性疾病传染性疾病
临床病理学临床病理学

背景情况:

败血症呈现出迅速发病和高死亡率,需要早期预后评估以改善结果.
败血症的延迟识别和治疗可能会导致败血症休克和死亡率的增加.
准确的预后工具对于治疗败血症的及时临床干预至关重要.

研究的目的:

评估顺序性器官衰竭评估 (SOFA) 评分,APACHE II 评分和白细胞 (WBC) 计数在预测败血症相关死亡率中的预后价值.
确定SOFA,APACHE II和WBC计数对败血症死亡风险的综合预测疗效.
为改善败血病患者的临床结果和治疗策略提供见解.

主要方法:

一项回顾性研究涉及139名在2021年1月至2023年12月期间被诊断为败血症的患者.
在28天的随访期内跟踪临床结果,将患者分为生存和死亡组.
用接收器操作特征 (ROC) 曲线来评估SOFA,APACHE II和WBC计数对死亡风险的预测准确性 (曲线下的面积 - AUC).

主要成果:

SOFA评分显示AUC为0.809 (P < .0001),而APACHE II评分显示AUC为0.806 (P < .0001),用于预测败血症死亡率.
白血细胞 (WBC) 计数在预测死亡风险时的AUC为0.689 (P = .004).
对SOFA,APACHE II和WBC计数的综合评估得出明显更高的AUC为0.861 (P < .0001),表明具有优异的预测价值.

结论:

SOFA评分,APACHE II评分和白细胞计数是败血症患者死亡率的重要预测指标.
SOFA,APACHE II和WBC计数的联合应用在评估死亡风险方面具有相当大的价值.
根据这些指标调整临床治疗计划可能会改善败血症患者的预后.

关键词:

在APACHE II分数中,分数是APACHE II.在SOFA中获得的分数是SOFA分数.白血球细胞计数WBC计数WBC计数死亡率的结果死亡率的结果.预测价值是一个预测值.这是一种血症.

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