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亚临床动脉样硬化和肉症:一个前性研究
Ezgi Yilmaz1, Ethem Murat Arsava, Mehmet Akif Topcuoglu
1Department of Neurology, Hacettepe University, Faculty of Medicine Hospital, Ankara, Turkey.
Medicine
|May 19, 2025
概括
皮症与动脉内膜介质厚度和斑块负担增加有关,这表明结构性动脉样硬化. 在肉患者中,动脉健康的功能性测量没有受到影响.
科学领域:
- 老年学是一门学科.
- 心血管医学 心血管医学
- 神经学 神经学
背景情况:
- 亚临床动脉样硬化和肉症之间的关系尚不清楚.
- 标志着肌肉损失的萨尔科佩尼亚可能与血管衰老有关.
研究的目的:
- 调查综合临床肉类症指数和亚临床动脉动脉样硬化之间的关联.
- 为了确定阴道动脉样硬化的结构和功能参数是否不同于sarcopenic个体.
主要方法:
- 一项前性研究涉及257名参与者 (平均年龄65岁).
- 使用Ishii分数来评估肉症.
- 亚临床性动脉动脉样硬化被通过超声波评估,使用动脉延伸度,内心介质厚度 (IMT) 和斑块负担.
主要成果:
- 麻症患者 (n=75) 年龄较大,瘦身,营养不良风险较高.
- 麻症患者的IMT (IMT-平均值,IMT-最大值) 和心血管斑块负担显著增加.
- 在sarcopenic和非sarcopenic组之间, carotid动脉延展性参数没有发现显著差异.
- 石井得分独立预测了更高的IMT-max和IMT-mean.
结论:
- 亚临床动脉样硬化的结构指数,特别是动脉IMT和斑块负担,在肉类患者中显著异常.
- 功能性动脉参数在各组之间没有差异.
- 在等待进一步研究验证之前,超声波动脉硬化指数可以作为缩症治疗的替代标记.
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