连续与间歇性输液养后食结肠切除术,一个试点随机控制试验
Peticha Tanprasert1, Phanuwat Tharathipphayakun2, Wasana Ko-Iam1
1Gastrointestinal Surgery Unit, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Clinical Surgical Research Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Clinical nutrition ESPEN
|May 19, 2025
概括
连续和间歇性结肠切割养策略在实现全养,胃肠道问题或代谢变化方面没有显著差异. 这项研究比较了上部肠道疾病患者的两种方法.
科学领域:
- 胃肠病学 胃肠病学
- 手术营养是指手术营养.
- 临床试验 临床试验
背景情况:
- 对上部胃肠道疾病而言,食凝肠术至关重要,但缺乏明确的术后食指南.
- 这项研究探讨了基于证据的养策略的必要性.
研究的目的:
- 为了比较连续与间歇性养策略的疗效后jejunostomy.
- 评估对实现充分养,胃肠道不良事件和代谢变化的时间的影响.
主要方法:
- 一个随机控制的非劣势试验试验,涉及40名上部肠道疾病患者.
- 患者被分配到连续或间歇性养组.
- 主要结局:达到完全养的时间 (30毫升/公斤/天);次要结局:胃肠道不良事件和代谢变化.
主要成果:
- 在连续和间歇组之间实现完全养的时间没有观察到统计学上显著的差异 (48 ± 0小时与50.4 ± 5.6小时,p = 0.080).
- 胃肠道不良事件,包括腹部不适和腹,在两组之间没有显著差异 (p = 1.000).
- 食策略之间代谢结果也没有显著差异.
结论:
- 连续性和间歇性养策略在结肠切除术后是相似的.
- 两种养方法都没有在养进步,胃肠道耐受性或代谢稳定性方面表现出优越性.
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