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使用DeepPolisher进行高精度组装抛光.

Mira Mastoras1, Mobin Asri1, Lucas Brambrink2

  • 1UC Santa Cruz Genomics Institute, University of California, Santa Cruz, California 95060, USA.

Genome research
|May 19, 2025
PubMed
概括

新的人工智能模型DeepPolisher通过将错误减少一半,显著提高了基因组组装精度. 它使用PacBio HiFi和牛津纳米孔技术数据进行精确的基层校正,增强生物研究.

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Spindle Assembly02:50

Spindle Assembly

Spindle assembly occurs through three, often coexisting, pathways – the centrosome-mediated pathway, the chromatin-mediated pathway, and the microtubule-mediated pathway – collectively contributing to form a robust spindle apparatus.
In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a microtubule array...