术后的SARS-CoV-2感染和术后并发症:在中国的一项单中心回顾性队列研究
Jia Zhan1, Fei Zhong2, LingYan Dai2
1Department of Anesthesiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
BMJ open
|May 19, 2025
概括
术后的SARS-CoV-2感染,特别是在手术后两周内,显著增加了术后并发症的风险. 随着感染和手术之间的时间间隔延长,风险就会减少.
科学领域:
- 传染性疾病 传染性疾病
- 外科手术的结果
- 流行病学 流行病学
背景情况:
- 欧米克朗变种的激增为经过外科手术后感染SARS-CoV-2的手术患者的管理带来了独特的挑战.
- 了解COVID-19感染相对于手术的时间的影响对于患者的安全至关重要.
研究的目的:
- 为了调查围绕手术的SARS-CoV-2感染和在Omicron流行浪潮期间的术后并发症之间的关联.
- 为了确定感染的时间是否会影响手术不良结果的风险.
主要方法:
- 追溯队列研究涉及7927名接受手术的成年患者.
- 多变量后勤回归分析了从手术到COVID-19诊断的间隔和术后并发症之间的关系.
- 术后并发症被定义为30天内不良事件的复合.
主要成果:
- 11.76%的患者经历了术后并发症.
- 术前和术后的COVID-19在手术后一周内与明显更高的并发症风险相关 (aORs从1.95到2.67).
- 随着手术和感染之间的间隔越长,风险就越低;老年患者,吸烟者,并发症患者和严重症状患者面临更高的风险.
结论:
- 在术后COVID-19和术后并发症之间存在显著的时间依赖关系.
- 量身定制的术前风险评估,加强术后监测和有效的COVID-19预防是必不可少的.
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