[治疗高血压患者的家庭血压在工作日到周末的变化研究]
1School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Zhonghua xin xue guan bing za zhi
|May 19, 2025
概括
在高血压患者的家庭血压往往在工作日增加,在周末下降. 肥胖和糖尿病等因素会影响这种模式,如果排除周末数据,会影响监测的准确性.
科学领域:
- 心血管医学 心血管医学
- 高血压管理 高血压管理
- 临床研究 临床研究
背景情况:
- 了解家庭血压 (HBP) 的日常变化对于有效的高血压管理至关重要.
- 以前的研究还没有完全阐明治疗高血压患者的周日到周末的HBP变化及其相关因素.
研究的目的:
- 在服用药物的高血压患者中调查周日与周末的HBP变化.
- 为了确定影响这些血压变化的因素.
- 评估排除周末HBP数据对监测结果的影响.
主要方法:
- 一项国家多中心前性注册研究,涉及3228名服用抗高血压药物的高血压患者.
- 收集的一般临床数据,办公室和基线HBP测量.
- 连续7天进行HBP监测,分析趋势,并使用回归进行因子识别和数据排除影响的一致性测试.
主要成果:
- 肝血压在平日 (周一至周五) 呈上升趋势,周末 (周六至周日) 呈下降趋势.
- 周末的血压并没有明显低于平日的血压,但周日的血压明显低于周五的血压.
- 超重/肥胖,饮酒或糖尿病患者表现出较小的HBP下降或从工作日到周末的增加. 排除2个周末日显示与1周监测一致 (Kappa=0.90),而仅排除周日显示轻微不一致 (Kappa=0.88).
结论:
- 接受治疗的高血压患者在工作日呈现HBP上升和周末下降的模式.
- 特定的患者亚组 (超重/肥胖,饮酒者,糖尿病患者) 显示周末HBP降低不那么明显.
- 排除周末HBP数据,特别是周日,可能会影响一周HBP监测结果的准确性.
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