发生性心力衰竭在活检证明的代谢功能障碍相关的脂肪性肝病患者中很常见,但未得到充分的认可
Kara Wegermann1, Fouad Chouairi2, Georgia Sofia Karachaliou1
1Division of Gastroenterology, Department of Medicine, Duke University Health System, Durham, NC, USA.
European journal of heart failure
|May 19, 2025
概括
与代谢功能障碍相关的脂肪性肝病 (MASLD) 患者心力衰竭 (HF) 的发病率很高. 在MASLD患者中,早期查和治疗HF的途径对于降低死亡率至关重要.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 内部医学 内部医学
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 越来越多地被认为是严重的健康问题.
- MASLD独立地与心力衰竭 (HF) 的风险增加有关.
研究的目的:
- 为了确定心力衰竭 (HF) 的发病率在活检证明的MASLD患者中.
- 为了确定与这种人群中HF发展相关的因素.
主要方法:
- 一项前性队列研究包括560名活检证明MASLD的患者.
- 对患者进行了平均11.0年的随访,以观察发生的HF.
- 多变量后勤回归被用来确定高频率的预测因子.
主要成果:
- 在随访期间,HF的发病率为17.9%.
- 另外47.9%的患者符合怀疑高血压的标准.
- 随着年龄和女性性别的增加,发生HF的风险更高.
结论:
- 活检证明的MASLD与高频率的HF有关.
- 在MASLD患者的疑似HF和正式诊断之间存在很大的差距.
- 实施HF查和护理途径可能会改善MASLD患者的治疗结果.
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