Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

536
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
536
Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

824
Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and signal-to-noise ratio for the analyte. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.
Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called collision-induced...
824

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Digital Revitalization of a Legacy Linear Ion Trap System.

Analytical chemistry·2026
Same author

Accessing Higher Order Mathieu Space Stability Zones to Narrow Isolation Widths Using Digital Quadrupole Time-of-Flight Mass Spectrometry.

Journal of the American Society for Mass Spectrometry·2025
Same author

A Hybrid Vacuum Flange RF Oscillator for Low-Cost Mass Spectrometry.

Journal of the American Society for Mass Spectrometry·2025
Same author

Efficient Coupling of Structures for Lossless Ion Manipulations with Ion Trap Mass Analyzers Using Phase Modulation.

Journal of the American Society for Mass Spectrometry·2025
Same author

Advancing Protein Analysis: A Low-Pressure Drift Tube Orbitrap Mass Spectrometer for Ultraviolet Photodissociation-Based Structural Characterization.

Analytical chemistry·2024
Same author

Ion confinement and separation using asymmetric electrodynamic fields in structures for lossless ion manipulations.

Rapid communications in mass spectrometry : RCM·2024

相关实验视频

Updated: May 21, 2025

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
08:40

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

Published on: January 20, 2022

4.2K

阶段调制以增加离子吞吐量用于离子移动性-飞行时间实验.

Nathan W Buzitis1, Daniel Wu1, Zackary Kinlein1

  • 1Department of Chemistry, Washington State University, Pullman, Washington 99164, United States.

Journal of the American Society for Mass Spectrometry
|May 19, 2025
PubMed
概括

阶段离子移动性光谱学通过增加工作周期的10倍,大大缩短了分析时间. 这种无损离子操纵 (SLIM) 结构的进步提高了效率,而不损失分离功率.

科学领域:

  • 分析化学 分析化学
  • 物理化学 物理化学
  • 频谱测量是一种光谱测量.

背景情况:

  • 无损离子操纵结构 (SLIM) 提供先进的离子分离.
  • 传统的SLIM方法通常具有有限的工作周期,影响分析吞吐量.
  • 整合SLIM与飞行时间质量分析仪对于全面分析至关重要.

研究的目的:

  • 为SLIM实施和评估一个基于阶段的门户计划.
  • 提高SLIM实验的分析效率和工作周期.
  • 评估分阶段封锁对分离能力和分辨能力的影响.

主要方法:

  • 为离子操纵开发基于阶段的关方案.
  • 阶段关门系统与6米SLIM设备和飞行时间质量分析仪的集成.
  • 阶段离子运动谱与信号平均 SLIM 实验的比较.

主要成果:

  • 与信号平均 SLIM 相比,相位离子流动性光谱学实现了 10 倍的工作周期的增加.
  • 分离能力和分辨能力在分阶段模式下保持不变.
  • 该方法允许代数或直接确定到达时间的整数.
关键词:
仪器化 仪器化 仪器化离子流动性光谱仪离子流动性光谱仪多重复合是一种多重复合.对于无损离子操纵的结构.飞行时间 MS 飞行时间旅行的波浪旅行.

更多相关视频

T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis
16:40

T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis

Published on: July 31, 2010

24.5K
Measurement of Ultrafast Vibrational Coherences in Polyatomic Radical Cations with Strong-Field Adiabatic Ionization
08:22

Measurement of Ultrafast Vibrational Coherences in Polyatomic Radical Cations with Strong-Field Adiabatic Ionization

Published on: August 6, 2018

6.8K

相关实验视频

Last Updated: May 21, 2025

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
08:40

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

Published on: January 20, 2022

4.2K
T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis
16:40

T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis

Published on: July 31, 2010

24.5K
Measurement of Ultrafast Vibrational Coherences in Polyatomic Radical Cations with Strong-Field Adiabatic Ionization
08:22

Measurement of Ultrafast Vibrational Coherences in Polyatomic Radical Cations with Strong-Field Adiabatic Ionization

Published on: August 6, 2018

6.8K

结论:

  • 基于阶段的门将显著提高SLIM的工作周期和离子效率.
  • 这种方法可以减少实验分析的持续时间,而不会影响分离.
  • 该方法可以很容易地集成到现有的离子流动性质谱仪器.