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Updated: May 23, 2025

Pooled CRISPR-Based Genetic Screens in Mammalian Cells
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Published on: September 4, 2019

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一个基于CRISPR/Cas9的增强高通量单细胞转录组学

Amitabh C Pandey1,2,3, Jon Bezney4,5,6, Dante DeAscanis5

  • 1Section of Cardiology, Tulane Heart and Vascular Institute, Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA. apandey@tulane.edu.

Nature communications
|May 19, 2025
PubMed
概括

单细胞CRISPRclean (scCLEAN) 是一种新的分子方法,通过去除丰富的转录来改善单细胞RNA测序 (scRNAseq). 这提高了低丰度转录的检测,揭示了更深层次的生物学见解.

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