头部和部皮质纤维瘤突起:广泛切除和重建的案例系列与文献审查
Skander Kedous1, Ameni Amri1, Alia Methnani1
1ENT Head & Neck Surgery Department, Salah Azaiz Institute, Tunis, Tunisia.
F1000Research
|May 20, 2025
概括
具有广泛边缘的激进手术切除对于治疗头部和部突起性皮质纤维素瘤至关重要. 这种方法,加上适当的重建,有效地降低了复发风险.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 皮肤病理学 皮肤病理学
背景情况:
- 皮质纤维瘤突起 (DFSP) 是一种罕见的,局部具有攻击性的软组织肉瘤.
- 头部和部的参与占DFSP病例的10-15%,由于解剖学的限制,造成了外科手术的挑战.
- 广泛的切除和复杂的重建通常是成功管理所必需的.
研究的目的:
- 介绍一系列在头部和部进行广泛的DFSP切除的案例.
- 分析手术边缘,重建策略,复发率和辅助治疗结果.
- 突出了实现DFSP管理的明确边际的重要性.
主要方法:
- 追溯分析四个头部和部DFSP病例,包括脸和头皮.
- 具有3-5厘米边缘的广泛局部切除,通过手术内冷截面分析证实.
- 使用自由板,局部板或二次意图进行重建,在某些情况下使用辅助放射治疗.
主要成果:
- 这四位患者都实现了负的外科手术边缘.
- 一名患者经历了需要修复手术的死.
- 在1至7年的随访期间,没有观察到局部复发.
结论:
- 具有广泛边缘的激进手术切除对于最大限度地降低头部和部DFSP复发风险至关重要.
- 自由板和局部重建技术提供了有利的功能和美学效果.
- 对于近边缘或深入入侵的病例,建议进行辅助放射治疗;长期随访至关重要.
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