透过因果推理的视角:共同变量选择的决定和陷
Gang Chen1, Zhengchen Cai2, Paul A Taylor1
1Scientific and Statistical Computing Core, National Institute of Mental Health, USA.
Aperture neuro
|May 20, 2025
概括
证明数据分析中包含共变量的合理性对于防止偏差和提高可重现性至关重要. 应用因果推断原则和透明报告可以提高神经影像和其他研究结果的稳定性.
科学领域:
- 神经成像分析分析神经成像分析
- 统计建模 统计建模
- 数据科学是数据科学.
背景情况:
- 在数据分析中包含共变量往往缺乏严格的理由,依赖于非正式的指导方针.
- 有问题的做法包括不分青红白的协变量合,缺乏合理性,以及不良的结果报告.
- 这些问题在神经成像中很常见,影响了反应时间,人口统计和形态测量等共变量的模型.
研究的目的:
- 强调在统计分析中证明共变量包含在统计分析中的关键重要性.
- 解决共变量选择和报告中的常见问题做法.
- 探索因果推理和领域知识在强大的数据分析中的作用.
主要方法:
- 统计和解释挑战在共变量纳入的审查.
- 应用因果推理原则对共变量选择.
- 偏差引入的分析 (高估,低估,掩盖,标志翻转,虚假效应).
主要成果:
- 如果不能证明共变量包含是合理的,可能会导致显著的偏见和虚假的发现.
- 域名知识对于共变量选择至关重要,比单独的统计措施更重要.
- 严格的门等做法可以引入选择偏见,类似于"双重浸泡".
结论:
- 建议包括明确的研究问题,合理的共变量处理,变量集中和透明的报告.
- 采用"突出,不要隐藏"的方法可以提高透明度和可重复性.
- 透明的共同变量关系描述支持在大型数据集 (例如,ABCD,英国生物库) 中开放的科学和可重复性.
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