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三管的粘弹性建模 chordae tendineae 组织组织

Li-Wei Liu¹, Chung-Hao Lee², Ankush Aggarwal³

¹Department of Engineering Science, National Cheng Kung University, Tainan 70101, Taiwan.

Applied mathematical modelling

|May 20, 2025

概括

这项研究使用一种新的粘弹性模型来模拟三管 (TV) 管 (chordea tendineae) 的机械行为. 该模型准确地预测了各种力量下的组织反应,改善了对电视功能的理解.

科学领域:

生物医学工程生物医学工程
组织力学组织力学
心血管研究研究心血管研究

背景情况:

三巴 (TV) 和肌对心脏门的功能至关重要.
了解它们的机械行为对于诊断和治疗与电视有关的疾病至关重要.

研究的目的:

在实验和理论上研究电视的机械行为.
开发和验证一种新的粘弹性模型用于TV chordae tendineae组织.

主要方法:

在TV chordae tendineae上进行了单轴机械测试.
开发了一个包含初始位移条件的非线性粘弹性模型.
衍生分析解决方案用于步骤和恒定速率的力应用.

主要成果:

观察到一个特征性的J形力位移曲线.
拟议的非线性粘弹性模型与实验数据相比显示出更高的性能.
灵敏度分析证实了初始条件对模型响应的影响.

结论:

开发的粘弹性模型准确地捕捉了TV chordae tendineae的机械行为.
这个模型为进一步研究电视病理生理学和治疗提供了宝贵的工具.
这项研究强调了初始条件对于准确建模软组织机制的重要性.

关键词:

科尔达肌 (Chordae tendineae) 是一种肌.爬行响应爬行响应爬行响应非线性通用凯尔文模型.单轴机械试验单轴机械试验粘弹性模型的粘弹性模型.

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Heart Valves

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...