局部止痛药与没有Entonox用于食道胃管腺镜的有效性比较:一项随机对照试验
Papiroon Noitasaeng1, Uayporn Kaosombatwattana2, Rojsirin Chaiwong3
1Department of Anesthesiology Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok Thailand.
DEN open
|May 20, 2025
概括
将Entonox添加到局部止痛药中显著提高了食道胃管透镜 (EGD) 的成功率和患者舒适度. 这种组合可以提高程序的耐受性和满意度,同时最大限度地减少副作用.
科学领域:
- 胃肠病学 胃肠病学
- 麻醉学 麻醉学
- 临床试验 临床试验
背景情况:
- 消化管胃管腺镜 (EGD) 对于诊断上部胃肠道问题至关重要.
- 患者在EGD期间的不适和焦虑可能会对程序结果产生负面影响.
- 有效的疼痛和焦虑管理对于成功的EGD手术至关重要.
研究的目的:
- 为了比较局部止痛药单独的疗效与在EGD期间与Entonox结合的疗效.
- 评估对手术成功,患者耐受性和满意度的影响.
- 评估Entonox与EGD局部止痛药联合使用的安全性.
主要方法:
- 一项前性,随机,双盲,受控试验,涉及211名患者.
- 患者接受了10%西洛卡因喷雾剂 (C组) 或10%西洛卡因喷雾剂与Entonox (E组).
- 测量结果包括手术成功,浴室胃镜耐受度,患者舒适度和满意度 (数值评分表).
主要成果:
- 与C组相比,E组的成功率显著提高 (76.2%对35.9%),耐受性更好 (82.9%对75.5%),舒适度提高 (86.7%对39.6%).
- 患者和内镜师在E组报告了更高的满意度.
- 使用Entonox与最小的副作用和较低的高血压和低心率有关.
结论:
- 将Entonox与局部止痛药相结合显著提高了EGD手术的成功,患者的耐受性和满意度.
- 这种组合提供了一种安全有效的策略,以减轻患者在EGD期间的不适和焦虑.
- 恩托诺克斯为改善EGD整体体验提供了有价值的补充.
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