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Updated: Jun 18, 2026

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Functional Imaging of Brown Fat in Mice with ¹⁸F-FDG micro-PET/CT

Published on: November 23, 2012

使用 [18F]FB(ePEG12) 12-Exendin-4 PET/CT 进行非侵入性胰岛素瘤诊断的定性和定量分析

Takaaki Murakami¹, Hayao Yoshida¹, Kentaro Sakaki¹

¹Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.

The Journal of clinical endocrinology and metabolism

|May 20, 2025

概括

使用18F-exendin-4的新PET/CT成像有效检测所有患者的胰岛素瘤. 这种新的方法显示出比传统方法更高的灵敏度,改善了高胰岛素血糖低血症的诊断和管理.

科学领域:

核医学就是核医学.
在瘤学瘤学.
内分泌学在内分泌学.

背景情况:

精确地定位胰岛素瘤是一个挑战.
传统的成像方法在胰岛素瘤检测方面存在局限性.

研究的目的:

评估新型18F-exendin-4 PET/CT在非侵入性胰岛素瘤检测方面的疗效.
将18F-exendin-4 PET/CT与传统的成像技术进行比较.

主要方法:

对患有高胰岛素低血糖症的患者进行前性单中心研究.
18F-exendin-4 PET/CT 在注射后60分钟和120分钟进行.
将PET/CT检测结果与传统成像和手术/病理学结果进行比较.

主要成果:

使用18F-exendin-4 PET/CT检测胰岛素瘤的100%灵敏度.
在瘤组织中显著更高的放射性追踪剂吸收.
与CT,MRI,EUS和SACT相比,检测率更高.

结论:

18F-exendin-4 PET/CT是一种敏感且有效的工具,用于胰岛素瘤的局部化.
为侵入性诊断程序提供可靠,非侵入性的替代方案.
有可能改善手术前定位和患者管理.

关键词:

类似葡萄糖的-1受体受体.胰岛素瘤是一种胰岛素.定子发射断层扫描 (PET).用β细胞成像进行的成像.

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Determining Glucose Metabolism Kinetics Using 18F-FDG Micro-PET/CT

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Published on: May 2, 2017

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Utilizing ¹⁸F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

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