案例 - 在克洛尼丁/阿尔金因生长激素刺激试验后,血栓保留的出血
Sami Mostafa1, Hailey H Frye2, Brent Cleveland1
1Department of Urology, University of Minnesota, Minneapolis, MN, United States.
概括
对生长激素 (GH) 的阿尔金宁和克洛尼丁测试可能会导致儿童患有疼痛性血与凝块保留. 这种以前没有报告的并发症需要仔细监测和管理.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 对于评估儿童生长激素 (GH) 缺乏症,氨酸和克隆氨酸刺激测试是常见的.
- 这些测试通常被认为是安全的,已知副作用包括暂时的,无痛的血.
研究的目的:
- 在GH刺激测试后报告一个显著的,痛苦的血与凝块保留的病例.
- 为了突出之前未经记录的阿尔金宁和克罗尼丁测试的并发症.
主要方法:
- 一个青春期前的孩子接受了标准的GH刺激测试,使用阿尔金宁和克隆尼丁.
- 记录了临床表现,诊断工作 (包括超声波) 和并发症的管理.
主要成果:
- 患者在测试后出现了疼痛的粗血流与凝块保留.
- 预期的门诊治疗导致膀血块的自发解脱,超声波证实了这一点.
结论:
- 氨酸和克洛尼丁GH刺激测试带有导致血栓保留严重出血的风险,这是以前没有描述的并发症.
- 这种潜在的不良事件可能需要医疗干预,需要临床意识.
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